Grade 5–8—Somewhere in the U.S., in a small farming community called Lowland County, a girl named Piper McCloud is born to a simple, God-fearing farmer and his wife. Piper has a special talent: she can fly. What follows is an uneasy mix of fantasy and science fiction that has plot points that are fairly derivative. When her talent for flying is discovered, a charismatic director of a special school takes Piper under her wing. She arrives at an amazing place with multiple floors and discovers a lot of other kids with extraordinary powers, too—as well as a nefarious plot to remove their special talents by altering their DNA.